Dermatitis herpetiformis presenting as pseudovasculitis
نویسندگان
چکیده
DH: dermatitis herpetiformis DIF: direct immunofluorescence EED: erythema elevatum diutinum INTRODUCTION Dermatitis herpetiformis (DH) is a cutaneous manifestation of gluten intolerance characterized by an intensely pruritic, papulovesicular eruption with a predilection for the extensor extremities, scalp, and buttocks. Because of its variable clinical presentation, DH can be a challenging clinical diagnosis. However, histopathology and immunofluorescence can provide vital data in confirming the diagnosis. We report a case of a 47-year-old patient who presented with clinical features resembling vasculitis but with classic histopathology and immunofluorescence findings for DH.
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BACKGROUND Dermatitis herpetiformis is an autoimmune disease typically characterized by pruritic vesicles located on the extensor surfaces. Classic disease consists of neutrophils in the dermal papillae. Additional histopathologic findings include fibrin deposition and edema within the dermal papillae. Subepidermal vesicles also may be present. Direct immunofluorescence demonstrates granular Ig...
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